Systems-Genetics.org
Systems genetics resource for the associations between SNP, gene, pathway (module) and phenotype.
BXD methods
Integrated systems genetics toolkit to probe gene function using multi-omics datasets from BXD mouse cohort. See more details about these methods from the Cell Systems paper, and the background of the BXD mouse cohort from here, here and here.
GeneBridge
GeneBridge predicts gene function and module connections using large-scale multi-species expression compendia. See
more details about GeneBridge
from the Genome Research paper.
BXD bile acid study
Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis
See more details about this study in the
Cell Metabolism paper.
ITP longevity study
Sex- and age-dependent genetics of longevity in a heterogeneous mouse population
See more details about this study in the
Science paper.
C. elegans RIAIL longevity study
High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular
regulators of lifespan. See more details about this study in the
preprint
Studies in CC founder strains
Metabolic study (HFD and CD)
Genetic background and sex control the outcome of high-fat diet feeding in mice
See more details about this study in the
iScience paper.
AKI-CKD (Folic acid nephropathy)
Mitochondrial and NAD+ metabolism predict recovery from acute kidney injury in a diverse mouse population
See more details about this study in the
JCI Insight paper.
NAFLD-NASH (Western diet and thermoneutrality)
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression
See more details about this study in the
Journal of Experimental Medicine paper.